Effect of coagulation factor concentrate administration on ROTEM® parameters in major trauma
نویسندگان
چکیده
منابع مشابه
Effect of coagulation factor concentrate administration on ROTEM® parameters in major trauma
BACKGROUND Purified coagulation factor concentrates, such as fibrinogen concentrate (FC) and prothrombin complex concentrate (PCC) are increasingly used as haemostatic therapy for trauma-induced coagulopathy (TIC). The impact of FC and PCC administration on ROTEM parameters among patients with TIC has not been adequately investigated. METHODS In this retrospective observational study, changes...
متن کاملGoal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate
INTRODUCTION The appropriate strategy for trauma-induced coagulopathy management is under debate. We report the treatment of major trauma using mainly coagulation factor concentrates. METHODS This retrospective analysis included trauma patients who received >or= 5 units of red blood cell concentrate within 24 hours. Coagulation management was guided by thromboelastometry (ROTEM). Fibrinogen c...
متن کاملROTEM®-guided coagulation factor concentrate therapy in trauma: 2-year experience in Venice, Italy
typically based on administration of allogeneic blood products, although the evidence supporting this approach is poor [1]. Fixed-ratio protocols have been proposed for administering fresh frozen plasma, red blood cells and platelets, but the optimal ratio has not been established and the speed of intervention may be more important [2]. In contrast to fi xed-ratio treatment, coagulation factor ...
متن کاملRotational thromboelastometry (ROTEM)-based coagulation management in cardiac surgery and major trauma.
P ( FOR MAJOR BLEEDING related to severe trauma, major surgery, or chronic anticoagulation, a rapid assessment of emostatic function is crucial so that optimal fluid replaceents and blood transfusion can be administered without deays.1-6 Although the safety of blood products with regard to viral transmission risks has improved in recent years,7,8 transfusions of allogeneic erythrocyte and plasm...
متن کامل[Coagulation management in major trauma].
In trauma associated coagulopathy, the initial treatment consists of hypothermia and acidosis have to be treated aggressively. Already in in the emergency room, fibrinogen deficiency can be detected frequently, in addition, colloids interfere with fibrin polymerisation. Under these aspects, the early administration of fibrinogen seems to be justified. Depleted coagulation factors can be substit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
سال: 2015
ISSN: 1757-7241
DOI: 10.1186/s13049-015-0165-4